虚弱作为一个动态过程,在一个多元化的老年人群中,有透析依赖的CKD
Nancy G Kutner1, Rebecca Zhang2
1Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Frontiers in nephrology
|September 7, 2023
概括
这项研究跟踪了两年来血液透析中慢性病的老年人的脆弱性变化. 了解脆弱过渡,包括改进,可以为策略提供信息,以促进这个脆弱人群的弹性.
科学领域:
- 老年病的医生 老年病的医生
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
背景情况:
- 虚弱是一种老年综合征,与老年人和患有慢性病 (CKD) 的人的不良结果有关.
- 脆性指数根据五个指标识别脆弱性:体重减轻,步行缓慢,力量低,疲劳和活动低.
- 脆弱状态之间的过渡 (例如,脆弱到前脆弱,前脆弱到强壮) 提供了预防和补救的见解,但对透析依赖的CKD群体的研究是有限的.
研究的目的:
- 描述老年人 (≥65岁) 维持血液透析 (HD) 的两年内虚弱状态演变的模式.
- 检查脆弱状态的变化如何与人口统计因素,非久坐行为和年龄友好4Ms卫生系统指标有关.
- 确定促进透析依赖性CKD的老年人恢复能力的潜在策略.
主要方法:
- 纵向队列研究,随访两年.
- 使用Fried脆弱性指数标准评估脆弱性状态.
- 根据年龄,性别,种族/民族,治疗年龄,身体活动和4M指标分析脆弱性演变模式.
主要成果:
- 在接受维护血液透析的老年人中,有脆弱状态演变模式的特征.
- 这项研究探讨了从脆弱转变为脆弱前/强壮的转变以及保持强壮状态.
- 人口因素,活动水平和4M指标与脆弱性过渡有关的分析.
结论:
- 了解脆弱性过渡,包括改善和稳定强壮状态,对于促进透析依赖性慢性脏病的老年人恢复力至关重要.
- 未来的纵向研究和临床试验应包括脆弱性和弹性测量.
- 提高弹性的策略可以通过随着时间的推移观察到的各种脆弱状态变化来告知.
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