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婴儿肠道微生物群殖民:产前和产后因素的影响,重点是饮食
Clara Suárez-Martínez1,2, Marina Santaella-Pascual1,2, Genoveva Yagüe-Guirao1,3
1Food Science and Nutrition Department, Veterinary Faculty, Regional Campus of International Excellence Campus Mare Nostrum, University of Murcia, Murcia, Spain.
Frontiers in microbiology
|September 7, 2023
概括
母亲的肠道微生物组是婴儿的第一个微生物注射剂. 了解生命早期的微生物发育是预防肥胖和过敏等疾病的关键.
科学领域:
- 微生物学 微生物学
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
背景情况:
- 母亲微生物群是婴儿肠道微生物殖民的主要来源.
- 围产和新生儿因素显著影响早期微生物发育.
- 肠道微生物群从出生到幼儿时期经历了显著的变化.
研究的目的:
- 审查关于早期肠道微生物群发展的证据.
- 确定影响微生物殖民和成熟的因素.
- 强调母婴微生物转移的重要性.
主要方法:
- 关于早期肠道微生物群的已发表证据的文献综述.
- 分析影响微生物殖民的因素 (产前,新生儿,产后).
- 专注于饮食和营养在怀孕和婴儿期的作用.
主要成果:
- 母婴因素 (饮食,抗生素,分娩方式,养) 塑造了婴儿肠道微生物组.
- 生命早期的肠道失调与增加疾病风险 (NEC,肥胖,过敏) 有关.
- 微生物多样性在出生后增加,稳定在3-5年.
结论:
- 优化母婴微生物转移对于婴儿健康至关重要.
- 生命早期肠道微生物群的发展会影响长期的疾病风险.
- 饮食和营养是早期肠道健康的关键可改变因素.
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