精密精神病学和研究领域标准:对临床试验和未来实践的影响
Leanne M Williams1,2, William T Carpenter3, Carrie Carretta4
1Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
CNS spectrums
|September 7, 2023
概括
精准精神病学通过整合神经科学和研究领域标准 (RDoC) 框架,提供量身定制的心理健康护理. 这种方法旨在改善精神疾病的分类,治疗和预防,解决全球心理健康需求.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 心理健康系统 心理健康系统
背景情况:
- 精神疾病给人带来了重大的社会和经济负担,COVID-19大流行加剧了这种负担.
- 目前诊断和治疗精神疾病的方法有局限性,需要新的方法.
- 随着COVID-19的流行,抑郁和焦虑的发生率有所增加,这凸显了对强大的心理健康系统的需求.
研究的目的:
- 审查全球对精密精神病学日益增长的兴趣.
- 探索国家卫生研究院设计的研究领域标准 (RDoC) 在推进精密精神病学的潜力.
- 讨论精神病学鼻科学的演变和采用跨诊断方法.
主要方法:
- 关于精密精神病学和RDoC框架的当前文献的审查.
- 分析RDoC在促进跨诊断和翻译研究方面的作用.
- 检查在临床研究中实施RDoC相关方法的挑战和机会.
主要成果:
- 精准精神病学,由神经科学,可以提高疾病分类,治疗选择和预防策略.
- RDoC为精神疾病的跨诊断方法提供了一个动态的框架.
- 多学科和以患者为中心的方法对于推进精密精神病学的发展至关重要.
结论:
- 精准精神病学有望改善精神疾病患者的治疗结果和生活质量.
- RDoC框架为研究和临床应用提供了一个有价值的,不断发展的结构.
- 精神病学鼻科学的持续合作和适应对于进步至关重要.
关键词:
精准医学是一门精准的医学.研究领域标准研究领域标准大脑电路成像成像系统认知 认知 认知诊断 诊断 诊断 诊断 诊断 诊断俄米克斯 (omicsics) 是一个电子产品.精神病学是一种精神病学.这是一种跨诊断的方法.治疗治疗治疗治疗治疗治疗更多相关视频
10:02Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
Published on: March 12, 2020
15.7K
10:32Development of a Virtual Reality Assessment of Everyday Living Skills
Published on: April 23, 2014
18.5K
相关概念视频
01:16Clinical Trials
6.8K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
6.8K
01:30Psychosurgery
78
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
78
01:11Clinical Trials: Overview
3.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.0K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
147
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
147
01:27Diagnostic and Statistical Manual of Mental Disorders (DSM)
80
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
80
01:26Psychosis: Goals of Pharmacotherapy
165
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
165