移植脏后腹:风险因素和结果的研究
A D Patil1, N G Saxena1, S B Thakare1
1Department of Nephrology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Journal of postgraduate medicine
|September 7, 2023
概括
移植脏后的腹可能会损害移植的功能. 由于腹而停止使用mycophenolate mofetil (MMF),增加了移植接受者 (KTRs) 慢性全移植损伤的风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植免疫学 移植免疫学
- 传染性疾病 传染性疾病
背景情况:
- 腹是移植接受者 (KTRs) 的常见并发症.
- 它可以导致显著的发病率,并影响长期的移植存活.
研究的目的:
- 评估KTRs中腹的发生率,原因和后果.
- 评估腹和mycophenolate mofetil (MMF) 戒断对全移植功能和慢性全移植损伤 (CAI) 的影响.
主要方法:
- 进行了对198名患有脏移植后腹的KTR的前性评估.
- 分析了腹发作的临床特征,病因和与急性异位移植功能障碍的关联.
- 结果包括慢性全移植损伤 (CAI) 和货币市场基金退出,评估货币市场基金退出对CAI风险的影响.
主要成果:
- 42.5%的KTR经历了腹,评估了140次发作.
- 感染病因,特别是Giardia和Cryptosporidium,在64.2%的病例中被确定.
- 在91.4%的发作中,腹复杂化了急性异位移植功能障碍,48.2%的接受者患上了CAI. 货币市场基金的退出与CAI的可能性更高有关.
结论:
- 移植后的腹会对移植的功能产生负面影响.
- 退出MMF,通常是持续性腹所必需的,增加了KTRs慢性全移植损伤的风险.
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