在军事生涯中累积的爆炸暴露会对创伤性脑损伤的恢复产生负面影响
Jason M Bailie1,2,3, Sara M Lippa4, Lars Hungerford1,3,5
1Traumatic Brain Injury Center of Excellence, Silver Spring, Maryland, USA.
Journal of neurotrauma
|September 7, 2023
概括
服务人员和退伍军人 (SMVs) 的终身爆炸暴露与创伤性脑损伤 (TBI) 后更糟糕的结果有关. 更高的爆炸暴露与增加的神经行为和PTSD症状相关,影响生活质量.
科学领域:
- 神经科学是一个神经科学.
- 军事医学 军事医学
- 创伤学 创伤学 创伤学
背景情况:
- 脑震荡后的伤害,包括爆炸暴露,越来越被认为是运动员和军事人员长期大脑健康的关键因素.
- 创伤性脑损伤 (TBI) 是服务人员和退伍军人 (SMVs) 的重要关注点,具有潜在的长期神经和心理后果.
研究的目的:
- 调查累计终身爆炸暴露 (LBE) 与经历TBI的中小企业的恢复结果之间的关系.
- 确定不同水平的LBE是否会影响神经行为症状,创伤后压力和创伤后的生活质量.
主要方法:
- 分析了558个中小企业的队列,这些企业有创伤病史.
- 根据自我报告的终身爆炸暴露 (LBE) 情况,参与者被分为三组:爆发天真 (n=121),低LBE (n=223,1-9次爆发) 和高LBE (n=214,>10次爆发).
- 评估了神经行为症状清单 (NSI),PTSD检查清单-平民 (PCL-C) 和TBI生活质量 (TBI-QOL) 评分,控制了人口统计和TBI相关因素.
主要成果:
- 与低和高LBE组相比,Blast Naive组报告了显著较低的NSI和PCL-C得分,表明神经行为和PTSD症状较少.
- 与Blast Naive组相比,在14个TBI-QOL尺度中的10个中,暴露于爆炸的SMV (低和高LBE组) 的生活质量较差.
- 在NSI,PCL-C或TBI-QOL测量上,在低LBE和高LBE组之间没有发现显著差异,这表明潜在的值效应或复杂的剂量反应关系.
结论:
- 在SMV中,终身爆炸暴露与TBI后的神经行为和创伤后压力症状的增加有关.
- 与爆炸事件相关的心理创伤可能会显著影响TBI后的症状表现和自我报告结果.
- 这些发现强调了在管理和了解军事人口中TBI恢复时考虑累积爆炸暴露的重要性.
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