用于剂量确定试验的贝叶斯层次模型,包括历史数据

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Updated: Jul 17, 2025

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
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Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Published on: September 4, 2017

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Linxi Han1, Qiqi Deng2, Zhangyi He3

  • 1School of Mathematics, University of Bristol, Bristol, UK.

Journal of biopharmaceutical statistics
|September 7, 2023
PubMed
概括

这项研究引入了一种新的贝叶斯方法,通过结合多个剂量组的历史数据来改进剂量发现试验. 这种方法旨在减少样本大小,同时保持药物开发中的统计能力.

关键词:
贝叶斯的等级框架是贝叶斯的等级框架.剂量检测方法 剂量检测方法试验之间的异质性.过去的借贷情况

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