在患有"短"体体的病例中,使用扩散张力成像进行定量胎儿MRI
R Corroenne1,2, D Grevent1,3, H Mahallati4
1URP FETUS 7328 and LUMIERE Platform, University of Paris, Paris, France.
概括
扩散张力成像 (DTI) 显示,短体 (SCC) 和Probst捆 (PB) 的胎儿表现出改变的白质微观结构. 没有PB的孤立SCC可能代表一个正常的变异.
科学领域:
- 神经成像是一种神经成像.
- 胎儿的发育 胎儿的发育
- 扩散张力成像 (DTI) 的使用.
背景情况:
- 短体 (SCC) 可能很难与正常发育变异区分开来.
- 带 (PB) 的存在可能表明体 (CC) 发育不良.
- 扩散张力成像 (DTI) 为白质微观结构分析提供了定量指标.
研究的目的:
- 为了比较SCC和正常CC的胎儿之间的DTI参数.
- 使用DTI,将SCC与PB (SCC-PB+) 与没有PB的SCC (SCC-PB-) 区分开来.
- 评估孤立的SCC-PB-是否代表一个正常的CC变异.
主要方法:
- 对22例SCC病例和66例对照患者的胎儿MRI和DTI数据的回顾性分析.
- 在整个CC及其地区测量的定量DTI参数 (FA和ADC).
- 使用ANOVA和ANCOVA进行统计比较,经过对混因子进行调整.
主要成果:
- SCC病例的CC尺寸明显小于正常对照.
- 与SCC-PB-和正常CC病例相比,SCC-PB+病例显示出明显较低的FA和较高的ADC值.
- 与正常的CC病例相比,SCC-PB-病例在FA和ADC中没有显著差异.
结论:
- 胎儿DTI可以在SCC-PB+病例中识别白质微观结构的改变.
- 孤立的SCC-PB-病例显示正常的DTI参数,表明正常发育的变体.
- DTI参数对于区分CC发育不良和SCC的正常变异有价值.
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