高的转录组可塑性驱动番茄中的酸盐饥饿反应
Viswanathan Satheesh1, Jieqiong Zhang1,2,3, Jinkai Li1,3
1Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Stress biology
|September 7, 2023
概括
了解番茄中的酸盐 (Pi) 饥饿,揭示了动态的转录基因变化,包括基因和异形表达转移. 这项研究对于开发具有更高Pi使用效率的作物至关重要.
科学领域:
- 植物分子生物学 植物分子生物学
- 营养物质压力生理学 压力生理学
背景情况:
- 酸盐 (Pi) 的可用性对植物生长和发育具有关键影响.
- 了解对Pi波动的分子反应对于提高作物Pi使用效率至关重要.
研究的目的:
- 在Pi饥饿下破译全球番茄的转录基因变化.
- 为了研究在Pi缺乏期间的基因和替代拼接变化.
主要方法:
- 使用定量时间序列RNA测序 (RNA-seq) 分析.
- 进行了转录基因分析,以确定动态变化.
主要成果:
- 七天后,Pi饥饿诱导了显著的形态生理反应,包括安托西亚宁积累和细胞死亡.
- 观察到全球转录组变化,包括基因和替代拼接变化,在Pi剥夺后7天达到峰值.
- 番茄表现出动态和复杂的转录基因适应低Pi压力.
结论:
- 这项研究突出了番茄转录基因组在应对低Pi压力时的动态性.
- 这些发现为研究人员研究番茄和其他作物的营养缺乏提供了宝贵的资源.
- 了解这些分子机制可以帮助开发具有提高Pi使用效率的作物.
相关概念视频
Transcription
147.1K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
147.1K
Riboswitches
8.2K
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
8.2K
Stringent Response in E. coli
31
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
31
Other Stress Responses in Bacteria
33
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
33
Overview of Transposition and Recombination
15.6K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
15.6K


