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Updated: Jul 17, 2025

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
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在人类前列腺癌和子宫内膜癌中SPOP突变的对立作用

Ludimila Cavalcante1, Sachin Kumar Deshmukh2, Jennifer R Ribeiro2

  • 1Novant Health Cancer Institute, Charlotte, NC.

JCO precision oncology
|September 7, 2023
PubMed
概括

斑点型POZ蛋白 (SPOP) 突变对前列腺癌和子宫内膜癌有不同的影响. 这些SPOP突变驱动了对立的分子和免疫变化,表明了不同的机制并指导了量身定制的疗法.

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