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Updated: Jul 17, 2025

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis
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Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis

Published on: January 7, 2017

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在XenoAptamers与目标蛋白质中,第五个字母,疏水性非自然基的严格相互作用

Michiko Kimoto1, Hui Pen Tan1, Ken-Ichiro Matsunaga1

  • 1Xenolis Pte. Ltd., 85 Science Park Drive, #02-05B, The Cavendish, Singapore 118259, Singapore.

Journal of the American Chemical Society
|September 7, 2023
PubMed
概括

研究人员通过修改非自然基来优化XenoAptamers. 新变体Ys和Bs显著增强了XenoAptamer与标蛋白的结合亲和力,显示出特定的分子内相互作用.

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