同时调节四种stilbene衍生物的吸收能力和抗氧化活性,利用替代效应:针对UVB辐射的理论和实验研究
Yajie Zhang1, Changjiao Shang1, Chaofan Sun1
1College of Science, Northeast Forestry University, Harbin 150040, China.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
|September 7, 2023
概括
这项研究研究了四种斯蒂尔衍生物的紫外线保护和抗氧化活性. 由于它们对抗紫外线辐射和自由基的强大性能,EHDB和HPTP对防晒的应用具有很好的潜力.
科学领域:
- 摄影化学的使用.
- 计算化学计算化学
- 皮肤病学 皮肤病学
背景情况:
- 臭氧层的消耗需要加强防晒策略.
- 紫外线 (UV) 辐射暴露会导致皮肤损伤,衰老,并增加皮肤癌症的风险.
- 斯蒂尔衍生物正在探索它们在防晒中的潜力.
研究的目的:
- 评估四种斯蒂尔衍生物 (EHDB,EDMB,EAPD,HPTP) 的紫外线吸收能力和抗氧化活性.
- 通过计算化学和实验方法评估它们适用于防晒配方的适用性.
- 提供对新型防晒开发的见解.
主要方法:
- 使用计算化学方法分析吸收光谱和抗氧化机制.
- 为了评估抗氧化能力,进行了DPPH激素清除实验.
- 分析包括原子转移 (HAT),连续质子损失电子转移 (SPLET) 和单个电子转移之后的质子转移 (SET-PT) 机制.
主要成果:
- 这四种斯蒂尔衍生物具有覆盖整个紫外线区域的吸收光谱,提供有效的UVB保护.
- EHDB和HPTP显示出最活跃的抗氧化剂位点 (O1H1).
- SPLET机制被确定为这些化合物的乙醇中首选的抗氧化途径.
结论:
- 由于其优越的抗氧化能力,EHDB和HPTP显示出防晒应用的巨大潜力.
- 实验DPPH结果补充了理论计算,证实了UV暴露前后的疗效.
- 这项研究为开发使用EHDB和HPTP的先进防晒提供了一种新的方法.
相关概念视频
01:42The Antenna Complex
6.0K
Plants and other photosynthetic organisms comprise pigments capable of absorption of direct sunlight. These pigments are present in the reaction center - the main site of photochemical reactions as well as in the antenna complex. Under average light conditions, the rate at which reaction center pigments absorb light is far below the electron transport chain's capacity. As a result, the reaction center alone cannot provide enough energy to drive photosynthesis. The photosynthetic efficiency...
6.0K
01:32UV–Vis Spectroscopy of Conjugated Systems
7.1K
Organic compounds with conjugated double bonds show strong absorption features in the UV–visible region of the electromagnetic spectrum attributed to π → π* electronic excitations. Generally, a UV–vis absorption spectrum is recorded as a plot of absorbance vs wavelength. The wavelength of maximum absorbance, which manifests as a peak in the absorption spectrum, is denoted as λmax.
One of the factors influencing λmax is the extent...
One of the factors influencing λmax is the extent...
7.1K
02:00Photoreceptors and Plant Responses to Light
20.5K
Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.
20.5K
01:35Mutations
38.2K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
38.2K
01:20Radical Autoxidation
2.2K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.2K
01:02Ultraviolet and Visible (UV–Vis) Spectroscopy: Overview
2.8K
Ultraviolet–visible (UV–visible or UV–Vis) spectroscopy is an analytical technique that investigates the interaction between matter and UV–Vis light within the electromagnetic spectrum. This method is widely used for its versatility, simplicity, and relatively quick data acquisition, making it valuable for both qualitative and quantitative analysis. When UV–Vis radiation passes through a material, molecules absorb light depending on the energy required for...
2.8K