厌恶的牛,催产素,以及避免感染的威胁
Martin Kavaliers1, Deanne T O Wah2, Indra R Bishnoi3
1Department of Psychology, University of Western Ontario, London, Canada; Graduate Program in Neuroscience University of Western Ontario, London, Canada; Department of Psychology and Neuroscience Program, University of Guelph, Guelph, Canada.
Hormones and behavior
|September 7, 2023
概括
陆地牛表现出令人厌恶的回避行为对感染牛的线索,类似于脊椎动物. 这种反应是由催产素 (OT) 和其受体同类分子调节的,这表明保留了感染回避机制.
科学领域:
- 动物学 动物学
- 神经科学是一个神经科学.
- 行为生态学 行为生态学
背景情况:
- 厌恶是一种基本的情感状态,驱使脊椎动物避免感染和病原体威胁.
- 这种情感状态会影响与寄生虫,病原体和感染同物种的相互作用.
研究的目的:
- 为了调查陆地是否表现出"令人厌恶的"回避行为,以应对感染个体的线索.
- 探索催产素 (OT) 和其受体同类在这些回避反应中的作用.
主要方法:
- 陆地牛 (Cepaea nemoralis) 暴露于用脂聚糖化物 (LPS) 处理的牛的粘液线索.
- 测量了行为回避和反感受反应.
- 评估了催产素受体对抗剂 (L-368,899) 对这些反应的影响.
主要成果:
- 暴露于LPS处理的牛粘液引起了陆地牛的剂量相关的行为回避和反感受.
- 暴露在LPS处理的粘液中的牛随后避免了陌生人.
- 催产素受体对抗剂量依赖地减弱了这些回避和反催产素受体反应.
结论:
- 陆地牛表现出类似厌恶的状态和对感染线索的行为回避反应,反映了脊椎动物的反应.
- 催产素及其受体同类似乎在调节避免感染行为的过程中起着保留作用.
- 这些发现表明,与病原体威胁相关的进化保守的厌恶状态和避免机制.
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