选择性沉默症与7q11.23重复综合征儿童的言语声音障碍之间的关系
Shelley L Velleman1, Vitor N Guimaraes2, Bonita P Klein-Tasman3
1Department of Communication Sciences and Disorders, The University of Vermont, Burlington.
Journal of speech, language, and hearing research : JSLHR
|September 7, 2023
概括
患有7q11.23重复综合征 (Dup7) 的儿童选择性沉默与语音障碍严重程度无关. 建议对焦虑症进行直接治疗,因为单独的语言治疗可能无法解决选择性沉默症.
科学领域:
- 遗传学 遗传学 是一个
- 神经发育障碍 神经发育障碍
- 语音语言病理学 语音语言病理学
背景情况:
- 7q11.23重复综合征 (Dup7) 是一种与语音障碍相关的遗传疾病,包括儿童语音失调 (CAS) 和选择性沉默等焦虑障碍.
- 在这个人群中,了解语音障碍严重程度和选择性沉默之间的关系对于有效的干预至关重要.
研究的目的:
- 调查语音障碍严重程度与Dup7儿童选择性沉默存在之间的关联.
- 探索Dup7儿童的语言能力,表达词汇,智力能力和焦虑障碍之间的潜在关联.
主要方法:
- 49名 (4-17岁) 确诊Dup7的儿童接受了评估,包括高盛-弗里斯托口音测试 (GFTA-2),表达词汇测试 (EVT-2) 和差异能力尺度 (DAS-II).
- 使用焦虑障碍访谈计划-家长 (ADIS-P) 进行的家长访谈是为了诊断焦虑障碍,包括选择性沉默和社会焦虑障碍.
主要成果:
- 与一般人群相比,参与者在GFTA-2 (65.67) 和DAS-II GCA (82.69) 上的标准平均得分较低,标准偏差更大.
- 45%的参与者被诊断为选择性沉默,59%的参与者被诊断为社会焦虑障碍.
- 在有选择性沉默或社会焦虑障碍的儿童和没有选择性沉默或社会焦虑障碍的儿童之间,没有发现语音障碍严重程度,词汇或智力能力的显著差异.
结论:
- 在患有Dup7的儿童中,选择性沉默和/或社会焦虑障碍与语音障碍严重程度,表达词汇或智力能力无关.
- 单独治疗语音障碍不太可能解决选择性沉默症;建议直接治疗焦虑症.
- 需要进一步的研究来确认这些发现是否适用于其他人群,例如患有异常性CAS的儿童.
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