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Updated: Jul 17, 2025

Visualizing Mitophagy with Fluorescent Dyes for Mitochondria and Lysosome
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溶解体通过依赖mTORC1的ATF4酸化调节线粒体的UPR

Terytty Yang Li1,2, Qi Wang3, Arwen W Gao3,4

  • 1State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Metabolic Remodeling and Health, Laboratory of Longevity and Metabolic Adaptations, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China. teryttyliyang@fudan.edu.cn.

Cell discovery
|September 7, 2023
PubMed
概括

溶解体通过真空H+-ATPase (v-ATPase) 和mTORC1信号,激活线粒体的应激反应. 这一过程涉及ATF4酸化,对线粒体健康和细胞存活至关重要.

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