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Author Spotlight: Multi-Layered Approach to Understand Postnatal Functions of Pancreatic Islets in Non-Human Primates
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综合表观基因组,全基因组序列和代谢组分析在2型糖尿病中发现了新的多基因组途径:中东研究

Noha A Yousri1,2,3, Omar M E Albagha4, Steven C Hunt5

  • 1Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar. nyousri@hbku.edu.qa.

BMC medicine
|September 7, 2023
PubMed
概括

这项研究结合了表观遗传学,全基因组测序和代谢学,以揭示2型糖尿病 (T2D) 在高患病率人群中的新生物机制. 研究结果揭示了新的T2D相关甲基基因和潜在治疗点的代谢途径.

关键词:
通过DNA甲基化.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.代谢学 代谢学 代谢学甲基化定量特征定位 (loci)多种组合的多种组合.奥米克斯网络 网络 网络路径 路径 路径卡塔尔生物银行 卡塔尔生物银行卡塔尔基因组项目2 型糖尿病 2 型糖尿病整个基因组序列的测序

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