克拉 (Mitragyna speciosa):怀孕前和怀孕期间使用的案例审查
Mary Ann Faucher1, Stephanie Morillos1, Polly Cordova1
1Women & Infants Specialty Health, Parkland Health, Dallas, Texas.
Journal of midwifery & women's health
|September 8, 2023
概括
克拉是一种植物性物质,越来越多地用于阿片类药物戒断,但其在怀孕期间的安全性在很大程度上是未知的. 迫切需要更多的研究来了解kratom.
科学领域:
- 药理学和毒理学 药理学和毒理学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 克拉 (Mitragyna speciosa) 具有类似阿片类药物的精神活性特性,并用于阿片类药物依赖.
- 阿片类药物使用障碍对孕产妇死亡率有很大影响,促使孕妇寻求像kratom这样的替代品.
- 有限的科学数据存在于克拉的影响,特别是在怀孕期间.
研究的目的:
- 审查当前关于怀孕期间使用 kratom 的科学证据.
- 突出潜在的风险和知识差距,关于 kratom 对孕产妇和胎儿健康的影响.
- 为了强调加 kratom 蔓延率的增加和缺乏监管对公共卫生的影响.
主要方法:
- 对现有病例报告和科学研究的文献综述.
- 对kratom的药理性质和报告的不良事件的分析.
- 审查与kratom相关的监管状况和公共卫生挑战.
主要成果:
- 关于 kratom 的治疗和不良影响的证据很少,特别是在怀孕期间.
- 案例报告表明,母亲使用 kratom 对新生儿的胎儿存在潜在风险.
- 缺乏监管,披露和测试给医疗保健提供者带来了重大挑战.
结论:
- 怀孕期间使用kratom的安全性尚未确立,需要进一步研究.
- 由于科学理解和监管有限,越来越多的kratom使用引发了公共卫生问题.
- 由于披露和测试限制,医疗保健提供者在管理使用kratom的患者方面面临挑战.
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