在患有慢性肠道病变的狗中对水解鱼类食进行随机对照试验
Kenneth W Simpson1, Meredith L Miller1, John P Loftus1
1Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Journal of veterinary internal medicine
|September 8, 2023
概括
饮食改变,无论具体成分如何,都能有效地治疗狗的慢性肠病 (CE). 水解鱼类饮食有助于蛋白质丧失肠病 (PLE) 病例的恢复,维持营养水平以实现长期缓解.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 狗胃肠病学 狗胃肠病学
- 营养科学 营养科学
背景情况:
- 饮食在犬类慢性肠病 (CE) 中的作用尚不清楚.
- 需要有效的CE饮食策略.
研究的目的:
- 将水解鱼 (HF) 和水解鱼与补充剂 (HF+) 饮食与控制饮食进行比较,以解决非蛋白质失去的CE (非PLE).
- 评估水解鱼类食对治疗蛋白质丧失CE (PLE) 的作用.
- 评估饮食对血清中可巴胺和叶酸水平的影响.
主要方法:
- 一个随机,盲目,受控的试验,涉及31只患有CE的狗 (23个非PLE,8个PLE).
- 狗接受了2周的测试饮食,响应者继续进行12周.
- 没有反应的人被转换为另一种饮食;长期随访26周.
主要成果:
- 83%的非PLE CE狗对最初的饮食有反应,饮食类型之间没有显著差异.
- 在26周后,100%的狗实现了持续缓解.
- 水解鱼类饮食促进了体重增加,改善了血清白蛋白,并有助于PLE犬的康复.
结论:
- 饮食修改,不论是抗原限制或特定补充剂,都会在非PLE CE.中诱导长期缓解.
- 饮食有效地维持了血清中的可巴胺和叶酸度.
- 化鱼类饮食对患有PLE的狗的临床康复和缓解有益.
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