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Updated: Jul 17, 2025

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在CHO细胞中S-Sulfocysteine的生物活性的机制性见解,使用多omics方法

Melanie Nguyen1,2, Maxime Le Mignon1, Alisa Schnellbächer1

  • 1Upstream R&D, Merck Life Science KGaA, Darmstadt, Germany.

Frontiers in bioengineering and biotechnology
|September 8, 2023
PubMed
概括

S-Sulfocysteine (SSC) 在CHO细胞中通过谷氨混合二硫化物形成代谢. 这一过程释放了氨酸 (Cys),在生物制造过程中支持细胞功能和平衡.

关键词:
查查查查查查查查查查查这是一种S-硫半氨酸,S-硫半氨酸.生物活动是生物活动.俄米克斯 (omicsics) 是一个电子产品.氧化还原控制是指氧化还原控制.

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Sulfur Assimilation01:20

Sulfur Assimilation

Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
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