揭开种族差距:不同种族群体之间的Helicobacter pylori感染清除
Rajmohan Rammohan1, Sai Greeshma Magam2, Melvin Joy2
1Gastroenterology, Nassau University Medical Center, East Meadow, USA.
Cureus
|September 8, 2023
概括
根据种族,H. pylori感染的清除时间不同,西班牙裔人经历的清除时间更长. 社会经济因素和语言障碍显著影响H. pylori根除成功,突出了健康差异.
科学领域:
- 医学微生物学 医学微生物学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 杆菌 (H. pylori) 感染导致慢性胃病,并与胃癌有关.
- 在H. pylori和胃癌发病率方面存在种族差异,非洲裔美国人面临更高的风险.
- 有效的H. pylori管理需要药物组合来克服耐药性和预防并发症.
研究的目的:
- 为了调查H. pylori感染清除率的种族差异.
- 确定影响不同种族群体H. pylori根除成功的因素.
- 为减少健康不平等提供文化敏感干预措施的信息.
主要方法:
- 对2009-2022年H. pylori感染数据的回顾性分析,按种族分类.
- 倾向性得分匹配,以平衡队列特征.
- 统计分析包括千平方,赔率比,卡普兰梅尔,Log Rank和二项逻辑回归.
主要成果:
- 分析了9288名感染H. pylori的患者队列,主要是女性 (64.7%).
- 西班牙裔患者的H. pylori疾病清除时间显著更长 (p=0.044).
- 语言障碍 (HR 0.346,p=0.043) 和教育状况 (HR 0.756,p=0.025) 是影响清除的关键因素.
结论:
- 在H. pylori清除率的种族差异需要文化敏感的干预措施.
- 社会经济地位和语言能力是H. pylori根除结果的关键决定因素.
- 解决这些差异对于改善医疗保健公平性和减少H. pylori感染的经济负担至关重要.
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