光学连贯断层扫描血管造影可以在患有贝塞特病的患者中作为一线眼科评估吗?
Dilhan Karaca1, Aynur Dıraçoğlu2, Feyza Önder2
1Department of Ophthalmology, Karadeniz Ereğli State Hospital, Zonguldak, Türkiye.
Archives of rheumatology
|September 8, 2023
概括
光学连贯断层扫描血管造影显示,贝赫塞特的血管性减少了.
科学领域:
- 眼科医生 眼科 眼科
- 血管生物学 血管生物学
- 类风湿病学 类风湿病学
背景情况:
- 贝切特病是一种多系统的炎症性疾病.
- 眼部干扰是一种常见且严重的并发症.
- 早期检测眼部变化对于管理至关重要.
研究的目的:
- 评估光学连贯断层扫描血管学 (OCTA) 在检测贝赫塞特病早期眼部变化的有用性.
- 为了比较Behçet的患者与没有眼睛参与和健康对照之间的微血管参数.
主要方法:
- 横截面研究包括22名眼部受损的贝切特患者,26名没有眼部受损的贝切特患者和22名健康对照.
- 使用OCTA分析状血管区 (FAZ) 区域,中央黄斑厚度和深层/表面毛细血管血管密度 (DCPVD/SCPVD).
- 参数包括总和副叶DCPVD和SCPVD.
主要成果:
- 与对照组相比,Behçet的眼部受影响的患者显示总和副叶DCPVD和SCPVD显著降低,FAZ区域更大.
- 毛细管密度与视力敏度正相关,与疾病持续时间负相关.
- 在没有眼部参与的贝切特患者和健康对照者之间没有观察到显著的微血管差异.
结论:
- 在Behçet的患者中,OCTA有效地证明了眼部参与的血管性下降.
- OCTA可以识别与贝塞特病相关的视网膜中的早期微血管变化.
- 与对照人群相比,OCTA在没有眼部参与的贝切特患者中没有显示出微血管差异.
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