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西利比宁通过调节肠微生物群和代谢物来减少体外甲的产生
Rui Liu1, Yueyu Shen2, Haokai Ma1
1College of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Frontiers in microbiology
|September 8, 2023
概括
在反动物料中补充西利比宁线性减少了肠道气体的产生,包括甲,并改变了反动物的微生物组成. 这表示silibinininin.
科学领域:
- 流体微生物学 流体微生物学
- 动物营养动物营养
- 环境科学环境科学
背景情况:
- 肠道甲生产是反动物农业温室气体排放的重要贡献者.
- 乳液发酵是一个复杂的过程,受饮食和微生物活动的影响.
- 乳中的一种化合物西利比宁具有潜在的生物活性,可能会影响功能.
研究的目的:
- 为了研究菌素在体外对乳头发酵参数的影响.
- 分析西利比宁对气产生的影响,包括甲.
- 为了确定silibinin对肠微生物群落结构和代谢物的影响.
主要方法:
- 在试验室发酵实验中,不同水平的西利比宁含量.
- 发酵参数,气体生产 (CO2,CH4,H2) 和挥发性脂肪酸的分析.
- 使用Illumina NovaSeq测序进行体微生物组分析.
- 差异代谢物和途径分析的非向代谢学.
主要成果:
- 锡比宁剂量依赖性降低了总气体产量,CO2,CH4,H2,以及酸与酸的比率.
- 增加pH值和改变挥发性脂肪酸概况被观察到与silibinin的添加.
- 观察到肠微生物的相对丰富性和上调的特定代谢物的显著变化.
- 干物质消化能力在0.15g/L及以上的西利比宁水平下降.
结论:
- 在体外,西利比宁有效地减轻了肠道甲的产生.
- 西利比宁改变了小麦芽发酵,微生物组成和代谢途径.
- 西利比宁作为一种新型的乳头甲抑制剂,可用于可持续的畜牧业生产.
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