对无症状的上部泌尿道尿癌的治疗策略
Deng Lin1, Yun Hong1, Zesong Yang1
1Shengli Clinical Medical College of Fujian Medical University and Department of Urology, Fujian Provincial Hospital, Fuzhou, China.
概括
无症状的上泌尿道泌尿道癌 (UTUC) 治疗与症状病例一致,需要风险分层进行适当的手术选择. 结果显示,无症状和症状的UTUC患者之间的瘤特异性死亡率相似.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 尿路上部泌尿道皮质癌 (UTUC) 和膀癌起源于尿道上皮质.
- 以前的研究表明,对于大多数无症状的膀瘤,可以通过尿道切除.
- 本研究侧重于无症状UTUC的治疗策略.
研究的目的:
- 调查无症状UTUC的临床病理特征.
- 评估无症状UTUC的手术方法.
- 确定无症状UTUC患者的最佳外科治疗策略.
主要方法:
- 对136名UTUC患者的回顾性分析.
- 组A:21个无症状的UTUC患者.
- 组B:有115名有症状的UTUC患者 (出血或腰部疼痛).
- 评估临床病理学特征,瘤学结果和手术方法.
- 与31名无症状膀泌尿道癌患者的比较.
主要成果:
- 主要治疗方法是彻底切除 (80.95%在A组,90.43%在B组).
- 无症状和症状的UTUC之间在病理阶段或等级上没有显著差异.
- 类似的瘤特异性死亡率:7.14% (A组) 与5.10% (B组) 在44.3个月的随访中位数.
- 与无症状膀泌尿腺癌相比,无症状的UTUC的阶段和等级更高 (p < 0.001).
结论:
- 无症状UTUC的治疗原则与症状UTUC是一致的.
- 基于临床阶段和其他参数的风险分层是至关重要的.
- 选择适当的外科治疗应遵循风险分层.
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