过量剂量教育和纳洛分发计划的设计由吸毒者和纳洛分销商提供信息
Michael Enich1,2, Rachel Flumo3, Stephanie Campos4
1Rutgers University School of Social Work, 120 Albany Street, New Brunswick, NJ 08901, USA.
Preventive medicine reports
|September 8, 2023
概括
使用毒品的人 (PWUD) 需要直接接触过量教育和纳洛分发 (OEND) 计划. 以社区为基础的项目优先考虑同行分配和PWUD投入对于有效的过量预防至关重要.
科学领域:
- 公共卫生 公共卫生
- 药物使用研究研究 药物使用研究
- 基于社区的参与式研究
背景情况:
- 过量服用流行病不成比例地影响使用毒品的人 (PWUD).
- 当前的过量剂量教育和纳洛分发 (OEND) 计划往往将PWUD排除在直接接收者之外.
- 现有的项目通常针对家庭,朋友或一般社区成员,而不是PWUD本身.
研究的目的:
- 了解PWUD和社区纳洛分销商对OEND计划设计的看法.
- 在特定的风险环境中确定OEND计划实施的最佳策略.
- 为制定更有效和更具包容性的OEND倡议提供信息.
主要方法:
- 采用基于社区的参与式研究模式.
- 与30名PWUD和纳洛分销商进行了半结构化的深度访谈.
- 用于分析面试数据的专题分析.
主要成果:
- 确定了关键主题:增加纳洛知识,优先考虑基于同行的纳洛获取,增强基于PWUD的OEND程序设计,扩大OEND程序范围.
- 参与者强调需要无处不在的纳洛可用性.
- 优先事项包括同行分配,与社区组织的整合,以及解决心理社会因素.
结论:
- PWUD和分销商主张以同行为主,以社区为基础的纳洛分销.
- OEND计划必须包含PWUD的新访问方法.
- 计划设计应以PWUD视角为中心,并直接分发社区,以获得最大的影响.
相关概念视频
Drug Abuse and Addiction: Pharmacological Phenomena
507
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
507
Nonlinear Pharmacokinetics: Overview
426
Nonlinear or dose-dependent pharmacokinetics is a phenomenon that occurs when the pharmacokinetic parameters of certain drugs deviate from linear pharmacokinetics at higher doses. These drugs do not follow the expected first-order kinetics, where the rate of drug elimination is directly proportional to the drug concentration. Instead, they exhibit a nonlinear relationship, which can be attributed to several factors.
Nonlinearity can arise due to the saturation of plasma protein-binding or...
Nonlinearity can arise due to the saturation of plasma protein-binding or...
426
Drug Dosage Regimen: Overview
3.6K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.6K
Opioid Receptors: Overview
995
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
995
Drug Delivery: Enteral Route
499
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
499
Prevention of Further Absorption of Poison
851
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
851


