在免疫检查点抑制剂治疗中患有小细胞肺癌的患者的伪进展性疾病
Wanshan Zhu1, Lexia Wu1, Jiaming Wu1
1Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, Zhongshan, Guangdong Province, People's Republic of China.
Cancer management and research
|September 8, 2023
概括
伪进展,小细胞肺癌 (SCLC) 免疫治疗中的一个令人担忧的反应,在评估治疗疗效方面提出了挑战. 本案例报告和综述提供了关于在高级SCLC中管理这种现象的见解.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 临床案例研究临床案例研究
背景情况:
- 小细胞肺癌 (SCLC) 的预后不好,治疗选择有限.
- 免疫疗法,包括免疫检查点抑制剂,在改善SCLC结果方面表现有前途.
- 伪进展,在免疫疗法期间明显的瘤扩大,使治疗评估复杂化.
相关概念视频
02:07Tumor Progression
6.4K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.4K
01:27Tumor Immunotherapy
554
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
554