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Updated: Jul 17, 2025

Label-free Single Molecule Detection Using Microtoroid Optical Resonators
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没有标签的光学生物传感:超越极限

Andrei V Kabashin1, Vasyl G Kravets2, Alexander N Grigorenko2

  • 1Aix Marseille Université, CNRS, UMR 7341 CNRS, LP3, Campus de Luminy-case 917, 13288, Marseille Cedex 9, France. andrei.kabashin@univ-amu.fr.

Chemical Society reviews
|September 8, 2023
PubMed
概括

无标签的光学生物传感正在超越研究限制. 使用光相和新材料的新方法实现了更高的灵敏度,超过了实时生物分子检测的传统标记技术.

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相关概念视频

Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
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