临床试验的未来 - 它是虚拟的吗?
Cho Ee Ng1,2, Sarah Bowman3, Jonathan Ling4
1Durham Bowel Service, County Durham and Darlington NHS Foundation Trust, Durham, DH1 5TW, UK.
British medical bulletin
|September 8, 2023
概括
分散的临床试验通过利用数字创新来实现远程访问,为低于最佳的参与者招募提供了解决方案. 这种方法增强了地理多样性,减少了患者的负担,提高了试验效率和可访问性.
科学领域:
- 临床试验方法论临床试验方法论
- 数字健康创新数字健康创新
- 医疗保健可访问性 医疗保健可访问性
背景情况:
- 传统的临床试验招聘面临重大挑战,影响及时的治疗进展.
- 不断发展的试验设计是有效交付,管理复杂的算法和适应文化变化的必要条件.
研究的目的:
- 探索分散的临床试验 (DCT) 的潜力,以克服招聘障碍.
- 审查最近的文献和行业经验,与传统方法一起实施DCT.
主要方法:
- 关于去中心化临床试验最近发表的研究的文献综述.
- 分析大型行业赞助的干预试验的实践经验,采用传统和分散的方法.
主要成果:
- 利用数字创新进行的分散的临床试验显示了改善参与者招聘和保留的潜力.
- 通过DCT,可以实现远程研究访问,从而有可能增加地理多样性并减少患者负担.
结论:
- 分散的临床试验代表了临床研究的一个有希望的演变,解决招聘和保留问题.
- 发展DCT的重点应该是扩大参与和减少医疗保健不平等.
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