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Updated: Jun 29, 2026

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来自犬类纳米孔组件的全基因组甲基化模式

Peter Z Schall1,2, Paige A Winkler3, Simon M Petersen-Jones3

  • 1Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA.

G3 (Bethesda, Md.)
|September 8, 2023
PubMed
概括

使用牛津纳米孔测序的新犬基因组组合提高了连续性,并揭示了缺失的保存基因. 这一进步有助于理解狗的遗传疾病和表观遗传特征.

关键词:
牛津的纳米孔在 de novo 组装.长读序列化 长读序列化甲基化处理的方法

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DNA Microarrays02:34

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...