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Updated: Jul 17, 2025

A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer
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A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer

Published on: September 13, 2022

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一种基于含有克洛法拉宾的阿巴美尔-PROTAC的尾酒治疗策略,用于增强癌症治疗

Zhenzhen Chen1, Mohan Chen1, Ran Liu1

  • 1State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing 210023, China. jing15209791@nju.edu.cn.

Chemical communications (Cambridge, England)
|September 8, 2023
PubMed
概括

一种具有核酸类比尾巴的新型PROTAC尾系统 (ApTCs-3X) 显示了增强的核酶抵抗力和强大的向蛋白质降解. 这种组合疗法改善了治疗结果,为临床使用推进了化向的仿真体.

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