根据儿童的系统性红血性狼严重程度,以斑点追踪回声心脏图测量左心室功能的下降
Masita I Rustam1, Reni Ghrahani2, Dzulfikar D L Hakim3
1Department of Child Health, Faculty of Medicine, Universitas Padjadjaran - Dr Hasan Sadikin General Hospital, Bandung, Indonesia.
Cardiology in the young
|September 8, 2023
概括
儿科系统性红斑狼 (SLE) 患者中等程度的疾病活动显示左心室功能减少与那些轻度活动. 斑点跟踪回声心脏图显示了中度SLE活动中的微妙心脏变化.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 类风湿病学 类风湿病学
- 医疗成像医学成像
背景情况:
- 系统性红斑狼 (SLE) 在儿童中经常呈现出侵略性.
- 儿科SLE中心脏参与可能是亚临床的.
- 斑点追踪回声心电图 (STE) 是检测心脏功能障碍的敏感工具.
研究的目的:
- 为了比较使用STE的左心室 (LV) 功能,在患有不同疾病活动的儿科SLE患者中.
- 根据疾病严重程度来确定心脏功能的差异.
主要方法:
- 49名儿科SLE患者的横截面研究.
- 使用墨西哥全身性狼红斑血性疾病活动指数 (MEX-SLEDAI) 评估疾病活动.
- 进行了常规和斑点跟踪回声心脏图.
主要成果:
- 在中度SLE活动 (-16.58) 与轻度活动 (-19.65) 中,全球纵向菌株显著减少.
- 射出分数,分数缩短和E/A比率在轻度和中度活动组之间没有显著差异.
- 81.96%的受试者是女性,平均年龄为15岁.
结论:
- 与轻度活动儿童相比,中度SLE活动的儿童表现出左心室功能受损.
- 在儿科SLE中,STE可以检测亚临床心脏功能障碍.
- 疾病活动与心肌应变的变化有关.
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