Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

2.7K
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin...
2.7K
Adhesion01:14

Adhesion

40.0K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
40.0K
Types of Membrane Protrusions01:28

Types of Membrane Protrusions

2.9K
The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth. These membrane protrusions are a result of cytoskeletal rearrangement. The most  widely observed cell protrusions include lamellipodia, pseudopodia, filopodia, microvilli, invadopodia, and podosomes. These protrusions can be of two types — static or dynamic.
The microvilli, an example of stable protrusions, are finger-like projections...
2.9K
Adherens Junctions01:24

Adherens Junctions

4.8K
Strong contact points between adjacent cells anchor them to each other, forming tissues. Such anchoring junctions are of two types –  adherens junctions and desmosomes. Adherens junctions are abundant in tissues such as  epithelium and endothelium, forming a continuous zone of adhesion called the adhesion belt. In other tissues, such as  heart muscle, they appear as clusters, linking the cells to produce coordinated heart muscle contraction.
Adherens Junctions are Dynamic
4.8K
Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

2.7K
In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...
2.7K
Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

2.7K
Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
2.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sphingosine-1-phosphate mitigates radiation-induced ovarian injury in rats by suppressing ferroptosis via activating the Nrf2-GCLC-GPX4 axis.

Journal of ovarian research·2026
Same author

Association between ASPECTS regions and clinical outcomes following endovascular therapy in patients with large infarcts: a post hoc analysis of the ANGEL-ASPECT trial.

Stroke and vascular neurology·2026
Same author

Construction and validation of a machine learning model for predicting early pregnancy in patients with polycystic ovary syndrome: a retrospective cohort study.

Journal of ovarian research·2026
Same author

"Internet+" Case-Based Learning Improves Perceived Learning Gains and Teaching Satisfaction in an Integrated Medical Curriculum: A Comparative Study.

Journal of medical education and curricular development·2026
Same author

Effect of Chloride Ion Concentration on the Corrosion Behavior of Mg-Gd-Y Alloys: An Experimental and First-Principles Calculation Study.

Inorganic chemistry·2026
Same author

Extracellular Vesicles as Immunomodulatory Mediators in Angiogenic-Osteogenic Coupling: Mechanistic Insights and Therapeutic Potential.

Advanced healthcare materials·2026

相关实验视频

Updated: Jul 17, 2025

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
07:55

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads

Published on: March 8, 2017

8.5K

预加载诱导的可切换粘附性

Chongwen Tu1, Keju Ji1, Jiahui Zhao1

  • 1State Key Laboratory of Mechanics and Control for Aerospace Structures, Nanjing University of Aeronautics and Astronautics, No. 29 Yudao Street, Nanjing, 210016, China.

Small (Weinheim an der Bergstrasse, Germany)
|September 8, 2023
PubMed
概括

研究人员开发了新的多层粘合剂 (MAs),通过调整预负载,快速切换粘合. 这些生物灵感粘合剂为实际应用提供了高效的附着和脱落.

关键词:
多层粘合剂的多层粘合剂预负荷诱导的粘附性结构参数结构参数可切换的粘附性可以切换.下面的侧面曲的曲

更多相关视频

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal
06:24

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

Published on: October 31, 2019

6.5K
An In Vitro Assay to Study Platelet Migration Using RGD-Functionalized Avidin-Biotin Tethers
05:43

An In Vitro Assay to Study Platelet Migration Using RGD-Functionalized Avidin-Biotin Tethers

Published on: November 8, 2024

395

相关实验视频

Last Updated: Jul 17, 2025

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
07:55

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads

Published on: March 8, 2017

8.5K
High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal
06:24

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

Published on: October 31, 2019

6.5K
An In Vitro Assay to Study Platelet Migration Using RGD-Functionalized Avidin-Biotin Tethers
05:43

An In Vitro Assay to Study Platelet Migration Using RGD-Functionalized Avidin-Biotin Tethers

Published on: November 8, 2024

395

科学领域:

  • 材料科学 材料科学 材料科学
  • 生物启发工程 生物启发工程
  • 粘附科学 粘附科学 粘附科学

背景情况:

  • 动物表现出高效的附着和脱落,激发生物粘合剂.
  • 目前的生物灵感粘合剂在执行器复杂性和切换速度方面面临挑战.

研究的目的:

  • 设计具有快速,无执行器开关能力的多层粘合剂 (MA).
  • 通过结构优化实现高粘合性切换比率.

主要方法:

  • 提出了一种多层粘合剂 (MA) 设计,具有背面,中间和底层.
  • 通过变化的预装载来研究粘附行为,诱导中间层变形和曲.
  • 优化结构参数以提高切换比率.

主要成果:

  • 通过调整预加载,实现高达136×的高开关比.
  • 仅通过结构设计和预装载操纵证明可切换的粘附性.
  • 整合了膜终结结构,以简化清洁,并保持微观结构的完整性.

结论:

  • 开发的MA提供了高效,快速和可切换的附着,没有复杂的执行器.
  • 设计显示了运输和其他需要控制粘附的应用的实际潜力.
  • 结构优化和预加载控制是实现高性能生物粘合剂的关键.