在动脉样硬化多民族研究中,酒精消费与子宫外脂肪之间的关联
Richard Kazibwe1, Parag A Chevli1, Joni K Evans2
1Department of Internal Medicine, Section on Hospital Medicine Wake Forest University School of Medicine Winston Salem NC USA.
Journal of the American Heart Association
|September 8, 2023
概括
过度饮酒和过度饮酒与子宫外脂肪增加有关,包括内脏和心周脂肪. 这种关系遵循J型模式,突出显示了超出中度摄入量对心血管健康的风险.
科学领域:
- 心血管疾病研究研究
- 营养流行病学 营养流行病学
- 医学成像分析 医学成像分析
背景情况:
- 宫外脂肪分布和酒精消费已成为心血管疾病 (CVD) 的风险因素.
- 酒精摄入模式和子宫外脂肪积累之间的特定关系仍然未得到充分探索.
研究的目的:
- 为了研究不同水平和模式的酒精消费和子宫外脂肪之间的关联.
- 分析与酒精摄入有关的心血管疾病风险的成年人宫外脂肪分布.
主要方法:
- 从多民族动脉样硬化研究 (MESA) 中对6756名参与者的横截面分析.
- 酒精摄入量分类:轻度,中度,重度,以前和终身禁酒; defined. 暴饮暴喝.
- 使用计算机断层扫描量化内脏,皮下,肌肉间脂肪,心周脂肪体积和肝脂肪.
主要成果:
- 与终身戒酒相比,大量饮酒与心周,肝脏和内脏脂肪的增加相关.
- 在酒精消费水平和子宫外脂肪之间观察到一个J形的关联.
- 过度饮酒与轻度至中度饮酒相比,与更高的子宫外脂肪积累有关.
结论:
- 酒精消费与子宫外肥胖有着J字形的关系.
- 无论是大量饮酒还是过度饮酒,都与更大的子宫外脂肪沉积有关.
- 这些发现强调了在评估心血管风险时考虑酒精消费模式的重要性.
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