糖尿病足患者的HbA1c水平升高与疾病严重程度和手术延长有关
Simay Akyüz1, Adile Begüm Bahçecioğlu Mutlu2, H Erhan Guven1
1Department of General Surgery Diabetic Foot, University of Health Sciences, Gulhane Research and Training Hospital, Ankara-Türkiye.
概括
诊断时高含糖血红蛋白 (HbA1c) 水平与糖尿病足的严重程度增加和截肢风险增加相关. 保持良好的血糖控制对于预防糖尿病患者的严重结果至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 血管外科 血管外科
- 糖尿病学 糖尿病学
背景情况:
- 糖尿病足是一种糖尿病 (DM) 的严重并发症,通常与外围动脉疾病和神经病变有关.
- 优化血葡萄糖和糖化血红蛋白 (HbA1c) 是糖尿病管理的基石治疗方法.
- 这项研究调查了2型糖尿病患者初始HbA1c水平与糖尿病足病严重程度之间的联系.
研究的目的:
- 评估诊断时HbA1c水平与糖尿病足病的严重程度之间的关系.
- 评估HbA1c水平与糖尿病足并发症所需的外科手术的程度之间的相关性.
- 分析糖尿病脚诊断时与血糖控制相关的治疗结果.
主要方法:
- 分析了301名被诊断患有糖尿病足部并需要手术的患者队列.
- HbA1c水平与瓦格纳和PEDIS (输液,范围,深度,感染,感觉) 分类系统相关.
- 根据患者的HbA1c值,评估了手术程序,治疗结果和截肢水平.
主要成果:
- 在HbA1c≥10.1%和瓦格纳4级糖尿病足 (DFU) 之间发现了显著的相关性 (90%).
- 在HbA1c ≥10.1%和PEDIS 3级之间观察到85%的显著关系.
- 增加的HbA1c水平显示出与更高的PEDIS等级的统计学意义上的关联,以及截肢水平的潜在增加.
结论:
- 诊断时HbA1c水平升高与糖尿病足病严重程度 (瓦格纳/PEDIS等级),手术程度和截肢风险增加有关.
- 在糖尿病足患者中,较高的HbA1c值与较大的组织损失相关.
- 加强对糖尿病治疗的坚持和改善血糖控制对于减轻糖尿病足病的严重程度和预防截肢至关重要.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
581
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
581
Diabetes Mellitus: Type 2 and Gestational
2.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.5K
Peripheral Artery Disease V: Postoperative Nursing Management
12
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
12
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
15
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
15
Traditional Level Of Health Care System
2.8K
The levels of care describe the services provided in the healthcare system. Accordingly, there are six levels of the traditional healthcare system in the US: preventive, primary, secondary, tertiary, restorative, and continuing healthcare. A nurse must understand how the healthcare industry organizes and provides services within these levels of care.
The preventive healthcare service includes tests for screening. Preventive health care services include identifying and reducing disease risk...
The preventive healthcare service includes tests for screening. Preventive health care services include identifying and reducing disease risk...
2.8K
Pathophysiology of Diabetes
980
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
980


