在法国多中心前性队列研究中,与长期COVID-19相关的因素
Nagham Khanafer1,2, Laetitia Henaff1, Sabrina Bennia2
1Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, CNRS UMR5308, ENS de Lyon, Lyon 1 University, CEDEX 07, 69364 Lyon, France.
International journal of environmental research and public health
|September 8, 2023
概括
长期COVID症状在某些患者中持续长达一年. 在初始COVID-19住院期间,肥胖和AST水平升高等因素预测了这些长期影响.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 内部医学 内部医学
背景情况:
- 许多人经历了COVID-19感染后的持续症状,影响了他们的长期健康.
- 了解长期COVID的流行率和预测因素对于患者管理至关重要.
研究的目的:
- 为了确定COVID-19后6-12个月持续的临床症状的患病率.
- 为了确定与长期COVID的发展相关的初始住院期间存在的因素.
主要方法:
- 一项涉及189名成年COVID-19患者的前性研究,这些患者住院于法国四所大学医院.
- 在COVID-19发病后6-8个月和1年进行了两次门诊随访.
- 使用多变量逻辑回归分析来确定相关因素.
主要成果:
- 肥胖 (BMI > 30 kg/m2),升高的AST水平和ICU住院与持续症状有关.
- 无呼吸,疼痛和更长的住院时间也与长期COVID在一年内有关.
- 衰老症与患长期COVID的风险降低有关.
结论:
- 在COVID-19感染后长达一年的时间内,观察到持续的临床症状.
- 疾病急性阶段的特定因素可以预测患有长期COVID的可能性.
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