斯皮诺辛A及其衍生物通过EGFR通路抑制结肠直肠癌细胞生长

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Kunjian Peng1, Zizheng Zou1,2, Jijia Li3

  • 1Department of Biochemistry and Molecular Biology, Hunan Province Key Laboratory of Basic and Applied Hematology, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Xiangya School of Medicine, Central South University, Changsha, 410008 Hunan, China.

Journal of natural products
|September 8, 2023
PubMed
概括

斯皮诺辛A (SPA) 和LM2I对结直肠癌细胞具有显著的抗增殖作用. 这些化合物抑制了表皮生长因子受体 (EGFR) 途径,为结直肠癌提供了潜在的新疗法策略.

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