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Updated: Jul 17, 2025

A Protocol for Phage Display and Affinity Selection Using Recombinant Protein Baits
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A Protocol for Phage Display and Affinity Selection Using Recombinant Protein Baits

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菌体显示两个不同的弹头,以抑制具有挑战性的蛋白质

Mengmeng Zheng1, Jianmin Gao1

  • 1Department of Chemistry, Merkert Chemistry Center, Boston College, 2609 Beacon Street, Chestnut Hill, Massachusetts 02467, United States.

ACS chemical biology
|September 8, 2023
PubMed
概括

这项研究引入了一个新的菌体库,用于发现治疗方法. 该图书馆具有双共价修饰,使得对TEV蛋白酶等酶的强有力的抑制剂的识别成为可能.

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DNA Bacteriophages01:26

DNA Bacteriophages

Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
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