Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Design Example: Analyzing Capacity Contours for Flood Risk Assessment01:17

Design Example: Analyzing Capacity Contours for Flood Risk Assessment

66
Flood risk assessment involves careful planning and analysis to ensure the safety of communities near water retention structures. Capacity contours are a vital tool in this process, as they illustrate the potential spread of water at specific levels in a given area. In the context of building a bund across a small valley, these contours play a critical role in evaluating the safety of nearby residential areas.In this example, the bund is intended to store stormwater in the valley. The engineers...
66
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

147
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
147
Relative Risk01:12

Relative Risk

208
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
208
Survival Curves01:18

Survival Curves

194
Survival curves are graphical representations that depict the survival experience of a population over time, offering an intuitive way to track the proportion of individuals who remain event-free at each time point. These curves are widely used in fields such as medicine, public health, and reliability engineering to visualize and compare survival probabilities across different groups or conditions.
The Kaplan-Meier estimator is the most common method for constructing survival curves. This...
194
Hazard Ratio01:12

Hazard Ratio

154
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
154
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

597
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
597

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Statistical Practices of Safety Monitoring: An Industry Survey.

Therapeutic innovation & regulatory science·2018
Same author

[Kinase-Glo luminescent kinase assay for in vitro determination of PKA activity].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology·2012
Same author

Functional characterization of an arrestin gene on insecticide resistance of Culex pipiens pallens.

Parasites & vectors·2012
Same author

MiR-23a inhibits myogenic differentiation through down regulation of fast myosin heavy chain isoforms.

Experimental cell research·2012
Same author

Let-7b inhibits human cancer phenotype by targeting cytochrome P450 epoxygenase 2J2.

PloS one·2012
Same author

Role of IKK/NF-κB signaling in extinction of conditioned place aversion memory in rats.

PloS one·2012

相关实验视频

Updated: Jul 17, 2025

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques
10:58

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Published on: January 2, 2011

10.2K

使用可视化来计划利益风险评估.

Michael W Colopy1, Lovemore Gakava2, Chen Chen3

  • 1Statistical Sciences & Innovation, UCB Biosciences, Inc, 4000 Paramount Parkway Suite 200, Morrisville, NC, 27560, USA. michael.colopy@ucb.com.

Therapeutic innovation & regulatory science
|September 8, 2023
PubMed
概括
此摘要是机器生成的。

利益风险评估计划 (BRAP) 积极概述药物开发评估,以确保利益超过风险. 本文详细介绍了一个假设的BRAP示例,指导研究药物的早期规划.

关键词:
决策方式 决策方式在MCDA中,MCDA是MCDA.规划 规划 计划 计划这是一个权衡的交易.不确定性 不确定性

更多相关视频

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.1K
Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

23.7K

相关实验视频

Last Updated: Jul 17, 2025

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques
10:58

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Published on: January 2, 2011

10.2K
Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.1K
Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

23.7K

科学领域:

  • 药物开发 药物开发
  • 监管科学是一种监管科学.
  • 临床试验规划 临床试验规划

背景情况:

  • 利益风险评估计划 (BRAP) 对于评估试验药物至关重要.
  • 建议在BRAP方面采取主动计划,而不是采取临时方法.
  • 关于构建主动BRAP的有限的出版指南.

研究的目的:

  • 为了说明积极的利益风险评估计划 (BRAP) 的结构和内容.
  • 在药物开发生命周期中提供BRAP的假设示例.
  • 突出BRAP过程中早期评估的重要性.

主要方法:

  • 开发一个假设的药物开发场景.
  • 在监管框架内对一系列计划评估进行可视化.
  • 医疗状况和当前治疗方法的早期评估的整合.

主要成果:

  • 假设的BRAP整合了决策里程碑的时间表和预先规定的评估.
  • 早期评估确定了研究药物的关键考虑因素.
  • 该示例展示了对利益风险评估的结构化,主动的方法.

结论:

  • 积极的BRAP开发对于药物开发中的高效和知情决策至关重要.
  • 在BRAP中的早期评估对于识别主要的利益风险因素至关重要.
  • 这篇文章提供了一个创建有效BRAP的实际框架.