在Hirschsprung病患者中持续阻塞性症状的预后因素在拉透后进行了拉透
Naisya Balela1, Aditya Rifqi Fauzi1, Ninditya Nugroho1
1Faculty of Medicine, Department of Surgery, Pediatric Surgery Division, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
PloS one
|September 8, 2023
概括
拉透手术的年龄较小与赫施普朗格病 (HSCR) 患者的持续阻塞性症状有关. 这一发现为管理HSCR结果的儿科外科医生提供了见解.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床研究 临床研究
背景情况:
- 赫施普朗格病 (HSCR) 患者在手术后往往有所改善,但有些人会出现持续的阻塞性症状.
- 之前对这些症状的研究主要集中在发达国家.
- 这项研究调查了发展中国家的HSCR患者队列中的预后因素.
研究的目的:
- 在希尔施普朗格病患者的拉透手术后,确定持续阻塞症状的预后因素.
- 提供特定于发展中国家人口的数据.
主要方法:
- 一项横截面研究分析了2017年1月至2022年1月期间114名HSCR患者的医疗记录.
- 收集的数据包括患者人口统计,手术细节和术后结果.
- 统计分析确定了与持续阻塞性症状相关的因素.
主要成果:
- 22%的HSCR患者在拉透后经历了持续的阻塞症状.
- 手术技术和最终手术时的年龄较小与这些症状有显著的关联.
- 多变量分析证实 pull-through时的年龄作为一个独立的预测因素 (OR=3.41,p=0.02).
结论:
- 在研究的HSCR人群中观察到持续阻塞性症状的中度频率.
- 拉透手术的年龄较小可能会增加持续阻塞性症状的风险.
- 研究结果为计划HSCR绝对手术的儿科外科医生提供了有价值的考虑.
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