单循环流感病毒疫苗产生肺CD8+Trm,与病毒变体发生交叉反应,并颠覆病毒逃生突变

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Ming Z M Zheng1, Tiong Kit Tan2, Fernando Villalon-Letelier1

  • 1Department of Microbiology and Immunology, The University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.

Science advances
|September 8, 2023
PubMed
概括

单周期流感病毒 (S-FLU) 疫苗接种在呼吸道中产生交叉反应的CD8+T细胞,在不促进病毒逃生突变的情况下提供对各种流感菌株的广泛保护.

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