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在扩散和多隔间磁共振成像研究中,无并发和复杂的单胆子双胎怀孕之间的胎盘差异

M Aertsen¹, A Melbourne², I Couck³

¹Department of Radiology, University Hospitals KU Leuven, Leuven, Belgium.

|September 8, 2023

概括

使用DECIDE模型的功能性MRI显示,在双胞胎输血综合征 (TTTS) 和选择性胎儿生长限制 (sFGR) 双胞胎双胞胎输血综合征 (MCDA) 怀孕中,胎儿氧度较低. 胎盘MRI参数在复杂的MCDA怀孕中不同.

科学领域:

产科和妇科产科和妇科
胎儿医学胎儿医学
医疗成像医学成像

背景情况:

双胞胎双胞胎输血综合征 (TTTS) 和选择性胎儿生长限制 (sFGR) 等并发症容易发生在单胞胎双胞胎 (MCDA) 怀孕中.
扩散-放松组合成像用于详细的胎盘评估 (DECIDE) 模型提供胎盘特异性分析,通过分离胎儿和母亲血液T2值来估计胎盘血氧和.

研究的目的:

调查与TTTS和sFGR相比,无并发症MCDA怀孕的胎盘中的扩散和放松差异.
评估DECIDE模型在复杂的MCDA怀孕中区分胎盘功能的实用性.

主要方法:

一项前性单心队列研究包括无并发症的MCDA,TTTS和sFGR怀孕.
进行了磁共振成像 (MRI) 与常规扩散权重成像 (DWI) 和组合放松计-DWI-intravoxel不连贯运动.
在DECIDE分析中量化了胎盘,胎儿和母体的参数.

主要成果:

传统的酒后驾驶 (DWI) 没有显示群体之间的显著差异.
与没有并发症的MCDA怀孕相比,DECIDE成像显示sFGR (较小的双胞胎) 和TTTS (双胞胎) 的胎盘氧和值明显较低.
平均T2放松时间在sFGR怀孕的小双胞胎与无并发的对照相比显著较低.

结论:

多隔间功能性MRI,特别是DECIDE模型,在怀孕中期发现了胎盘MRI参数的显著差异.
这些发现强调了先进的MRI技术在复杂的MCDA怀孕中检测胎盘功能障碍的潜力.

关键词:

功能性核磁共振成像 (MRI) 是一种功能性核磁共振成像.磁共振成像技术磁共振成像技术单胎怀孕是一种单胎怀孕.胎盘胎盘胎盘胎盘选择性的胎儿生长限制双胞胎输血综合征 - 双胞胎输血综合征

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