皮克林乳液通过三元复合物稳定,包括黄素修饰的和具有不同电荷量的多糖类,用于封装β-胡卜素
Deyi Zhou1, Yuelin Xin1, Baoguang Wu1
1College of Biological and Agricultural Engineering, Jilin University, Changchun 130022, Jilin Province, PR China.
Food chemistry
|September 8, 2023
概括
这项研究开发了新的抗氧化剂皮克林乳液,使用被多糖覆盖的-曲素纳米颗粒. 这些乳液有效地保护了β-胡卜素,并提高了其生物可用性.
科学领域:
- 食品科学与技术 食品科学与技术
- 材料科学 材料科学 材料科学
- 营养药化学 营养药化学
背景情况:
- 像β-胡卜素这样的脂性营养品容易降解和氧化.
- 开发有效的传递系统对于提高其稳定性和生物可用性至关重要.
- 扎因蛋白和黄素具有抗氧化特性,但需要适当的封装策略.
研究的目的:
- 创建新的抗氧化剂皮克林乳液,以改善脂友性营养素保护.
- 调查-曲素复合物和多糖合物涂层在乳液性能上的作用.
- 为了提高封装β-胡卜素的稳定性和体内生物可访问性.
主要方法:
- 齐恩被黄素修饰,形成共价和非共价复合物.
- 三级纳米粒子是通过涂上阿拉伯或卡拉雅来覆盖-库尔库明复合体而形成的.
- 评估了抗氧化活性,紫外线降解,脂质氧化和体外胃肠道消化.
- 贝塔胡卜素被用作封装的模型脂性营养药.
主要成果:
- 覆盖着多糖的zein-curcumin纳米颗粒形成了稳定的皮克林乳液.
- 加上黄素显著降低了β-胡卜素的紫外线降解和脂质氧化.
- 基于gum karaya的乳液显示出自由脂肪酸释放的优异延迟.
- 贝塔胡卜素的生物可用性得到显著改善,达到高达38%的生物可用性.
- 带有弱电荷的多糖和共价-黄素结合显示出优异的性能.
结论:
- 新型抗氧化剂皮克林乳液为脂性营养药提供了极好的保护.
- 选择多糖电荷和结合类型会影响乳液稳定性和生物可访问性.
- 这种方法提供了一个有希望的策略,以提高营养药的交付和有效性.
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