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Updated: Jul 16, 2025

Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO
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Published on: December 28, 2019

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损坏的线粒体会招募效应器NEMO来激活NF-κB信号传递

Olivia Harding1, Elisabeth Holzer2, Julia F Riley1

  • 1Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.

Molecular cell
|September 8, 2023
PubMed
概括

损坏的线粒体会触发天生的免疫反应. 核因子kappa B (NF-κB) 效应分子 (NEMO) 被招募到受损的线粒体中,启动与线粒细胞衰变并行的炎症信号通路.

关键词:
这就是ALS.这就是NEMO.在 NF-κBB 中.NF-κB 效应分子分子停车场可以停车.帕金森病是帕金森氏症的一种疾病.在SQSTM1/p62中使用.骨髓缩侧面硬化症 (ALS) 是一种细胞的压力是细胞的压力这是先天免疫力.线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.神经退行症的神经退行症神经炎症是一种神经炎症.选择性尿素核因子kappa B B阶段分离的相位分离.在任何地方都是无处不在的.

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