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Updated: Jul 16, 2025

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综合基因精细测绘和多组学数据,揭示了高血压的候选效应基因

Stefan van Duijvenboden1, Julia Ramírez2, William J Young3

  • 1William Harvey Research Institute, Barts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, EC1M 6BQ London, UK; Institute of Cardiovascular Science, University College London, London, UK; Nuffield Department of Population Health, University of Oxford, Oxford, UK.

American journal of human genetics
|September 8, 2023
PubMed
概括

研究人员通过将遗传数据与组织特定的调节信息相结合,确定了436个适用于血压调节的候选基因. 这项研究促进了对BP相关遗传位点的理解,并揭示了潜在的新药标.

关键词:
在GWAS中,GWAS就是GWAS.血压 血压 血压 血压定位化,定位化的地方.毒品目标是毒品的目标.我们的eQTL是eQTL.效应基因是指效应基因.表观遗传学注释表观遗传学注释精细地图的绘制.在pQTLTL中,pQTL是指pQTL.

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