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Updated: Jul 16, 2025

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在Src酶中对药物耐药性的规模分析揭示了自抑制和催化域动态的调节网络合

Sujata Chakraborty1, Ethan Ahler2, Jessica J Simon1

  • 1Department of Chemistry, University of Washington, Seattle, WA 98195, USA.

Cell chemical biology
|September 8, 2023
PubMed
概括

了解酶抑制剂耐药性对于癌症治疗至关重要. 这项研究揭示了Src氨酸激酶突变体中的新型耐药性机制,揭示了药物开发的新途径.

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