一种来自Epiphyllum oxypetalum (DC.) 的多糖. 哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈 和其免疫调节活性
Qiu-Yue Ma1, Qian-Da Xu1, Nan Chen1
1Department of Food Engineering, Sichuan University, Chengdu 610065, PR China.
International journal of biological macromolecules
|September 8, 2023
概括
来自Epiphyllum oxypetalum (EOP) 的新型多糖体显示出显著的免疫调节作用. 这种复杂的碳水化合物增强了巨细胞的活动和细胞因子的产生,显示了食品和药物应用的潜力.
科学领域:
- 生物化学 生物化学
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 多糖因其多样化的生物活动而闻名.
- 埃皮菲勒姆 (Epiphyllum oxypetalum) 是一种具有传统药用用途的植物.
- 了解植物性多糖的免疫调节潜力对于开发新疗法至关重要.
研究的目的:
- 从Epiphyllum oxypetalum中分离和鉴定一种多糖 (EOP) 的特征.
- 评估EOP在体外和体内免疫调节活动.
- 探索EOP在食品和医药行业的潜在应用.
主要方法:
- 使用多光谱分析对EOP进行隔离和结构阐明.
- 在RAW 264.7细胞上进行体外测试,以评估巨细胞的增殖,细胞和细胞因子的产生 (NO,TNF-α,IL-6).
- 使用斑马鱼进行体内研究,以评估EOP对巨细胞消化细胞的作用.
主要成果:
- EOP被确定为一个复杂的多糖,其分子量为5.77 × 10^6 Da,由拉姆诺斯,阿拉比诺斯,银和银酸组成.
- 在体外,EOP显著增加了巨细胞的增殖和细胞能力.
- EOP促进了氧化,瘤亡因子-α和介质素-6.6的产生.
- 在体内研究证实了EOP在斑马鱼中增强巨细胞消化能力.
结论:
- EOP具有复杂的结构,并表现出显著的体外和体内免疫调节活性.
- EOP增强了巨细胞的功能,包括增殖,细胞和细胞因子的释放.
- 研究结果表明,EOP在食品和医药行业具有重要的应用潜力.
关键词:
埃皮菲勒姆氧佩塔卢姆 (DC.) 是一个植物. 哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈免疫调节活性 免疫调节活性它是一种多糖化合物.结构性表征结构性表征斑马鱼是一种斑马鱼.更多相关视频
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