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在评估卫生系统对1型糖尿病管理的干预措施的研究中测量的结果:一个范围审查
Jessica Hanae Zafra-Tanaka1,2, Adela Del Valle1, Antonio Bernabé-Ortiz1,3
1CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
Diabetic medicine : a journal of the British Diabetic Association
|September 8, 2023
概括
关于1型糖尿病管理干预措施的研究表明,重点是临床结果,如HbA1C,而不是患者报告的措施. 研究很少评估所有推结果,测量工具各不相同,影响了可比性.
科学领域:
- 内分泌学和新陈代谢学
- 医疗保健服务研究 医疗服务研究
- 临床试验方法论 临床试验方法论
背景情况:
- 1型糖尿病的管理需要全面的结果评估.
- 一个核心结果集 (COS) 为一致的研究提供了必要的指标.
- 现有研究可能与COS建议不一致.
研究的目的:
- 为了比较卫生系统对1型糖尿病的干预报告的结果,用定义的COS.
- 确定1型糖尿病研究中常见的和报告不足的结果.
- 评估1型糖尿病研究中结果测量的一致性.
主要方法:
- 在PubMed,EMBASE和CENTRAL中对2010-2021年的研究进行系统的文献搜索.
- 根据1型糖尿病的COS提取和分类报告的结果.
- 对结果频率和测量一致性的分析.
主要成果:
- 包括187项研究,重点关注患有1型糖尿病的儿童和成人.
- 糖化血红蛋白 (HbA1C) 和自我管理是最常测量的.
- 糖尿病酸性糖尿病和临床参与是最少测量的;没有研究报告了所有COS结果.
- 不一致的测量工具被用于相同的结果.
结论:
- 针对1型糖尿病的卫生系统干预主要报告临床结果,而不是患者报告的措施.
- 目前的研究实践与COS建议有所不同,这凸显了对标准化的需要.
- 结果测量的变化阻碍了研究结果的可比性和综合性.
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