在参加瑞典反流试验的儿童中,膀功能的纵向随访
U Sillen1, S Hansson1, S Jernmark1
1From the Pediatric Uronephrology Center, Department of Pediatrics and Department of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
膀和肠道功能障碍 (BBD) 随着时间的推移,膀和肠道反流 (VUR) 儿童的症状下降,青少年女孩主要受到影响. BBD和功能障碍排泄症状 (DVS) 与复发性尿路感染 (UTI) 有关.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 儿科脏病学 儿科脏病学
- 儿童膀功能障碍 儿童膀功能障碍
背景情况:
- 儿童的膀外流 (VUR) 通常与膀功能障碍有关.
- 这种膀功能障碍在青春期的长期持续程度尚不清楚.
研究的目的:
- 为了评估膀和肠道功能障碍 (BBD) 在有VUR病史的儿童中持续到青春期的持续性.
- 分析BBD亚组及其与复发性尿路感染 (UTI) 的关联.
主要方法:
- 从瑞典反流试验 (SRT) 中对儿童的纵向随访.
- 膀功能使用验证的BBD问卷和多个时间点的尿液流量计进行评估.
- 计算了膀过活 (OAB) 和功能障碍排泄症状 (DVS) 的子诊断.
主要成果:
- 儿童早期BBD的患病率从37%下降到青春期的23%.
- 功能障碍排泄症状 (DVS) 持续存在,而过度活性膀 (OAB) 在青春期显著下降.
- 复发性尿路感染在BBD患者中更常见,BBD主要影响青少年女孩.
结论:
- 在患有VUR的儿童中,BBD的患病率随着年龄的增长而下降.
- 有VUR病史的青少年女孩更有可能患BBD和复发性尿路感染.
- 功能障碍排空症状 (DVS) 是该队列持续性BBD的重要组成部分.
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