癌症患者运动能力较低的预测因素
Ruben Evertz1,2, Christine Diehl1,3, Katharina Gödde1
1Department of Cardiology and Pneumology, University of Göttingen Medical Center (UMG), Georg-August-University Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.
Scientific reports
|September 8, 2023
概括
维持运动能力对于癌症患者至关重要. 较低的运动能力与贫血和升高的hs Troponin T有关,而较高的手握强度表明更好的能力.
科学领域:
- 在瘤学瘤学.
- 心脏病学 心脏病学
- 运动生理学 运动生理学
背景情况:
- 保持运动能力对于癌症患者的生活质量和自决能力至关重要.
- 在接受治疗的癌症患者中,运动能力的决定因素尚不清楚.
- 这项研究调查了在治疗期间影响不同类型癌症运动能力的因素.
研究的目的:
- 确定正在接受或即将接受治疗的癌症患者的运动能力的关键决定因素.
- 探索该群体临床参数与运动能力之间的关系.
主要方法:
- 在253名癌症患者中使用6分钟步行测试 (6-MWT) 评估运动能力.
- 进行心声回声,体检,心电图,手握强度 (HGS) 测量和实验室测试.
- 利用多变量后勤回归来识别运动能力受损的独立预测因素.
主要成果:
- 较低的运动能力与年龄较大,降低的HGS,较低的血红蛋白和升高的hsTroponin T和NT-proBNP有关.
- 贫血 (OR 6.172) 和增加的hs Troponin T (OR 3.077) 是运动能力受损的独立预测因素.
- 增加的HGS与较低的运动能力风险降低有关 (OR 0.896).
结论:
- 贫血和升高的hs Troponin T是癌症患者运动能力降低的重要预测因素.
- 手握强度是运动能力的重要指标.
- 查升高的hs,Troponin T和降低的HGS可以帮助识别风险患者进行主动干预.
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