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晚期早产和儿童时期的成长轨迹:一个关联的回顾性队列研究
Yulika Yoshida-Montezuma1, David Kirkwood2, Branavan Sivapathasundaram2
1Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street W, Hamilton, ON, L8S 4L8, Canada.
BMC pediatrics
|September 8, 2023
概括
晚期早产的婴儿的体重轨迹与满期婴儿的体重轨迹相似,但在第一年增高速度更快. 需要进一步的随访,以评估与这些生长差异相关的长期健康风险.
科学领域:
- 儿科生长与发展 儿科生长与发展
- 新生儿医学 新生儿医学
- 心血管健康研究 心血管健康研究
背景情况:
- 加快的产后生长与不良的成人心血管健康有关.
- 与满期婴儿 (≥39周) 相比,晚期早产婴儿 (34-36周) 的生长轨迹尚不清楚.
- 了解这些差异对于评估长期健康结果至关重要.
研究的目的:
- 评估妊娠年龄组 (晚期早产 vs 满期) 与儿童生长轨迹之间的关联.
- 分析2006-2014年间出生的儿童从出生到14岁的体重和身高发展情况.
- 根据早期生长模式,为潜在的长期健康影响提供信息.
主要方法:
- 使用TARGet Kids!进行的回顾性队列研究 初级保健网络数据.
- 包括单独出生,重复测量体重和身高/长度,从出生到14岁.
- 应用零碎线性混合模型来分析基于时间年龄的生长轨迹.
主要成果:
- 与满期婴儿相比,早产晚期的婴儿从出生到14岁的平均体重和身高较低.
- 在晚期早产和全产组之间,体重轨迹在很大程度上是相似的,在84个月后略有差异.
- 晚期早产婴儿在生命的头12个月内表现出更快的身高增长率.
结论:
- 晚期早产与明显的生长模式有关,包括较快的早期身高增长,与满期出生相比.
- 虽然体重轨迹显示出相似性,但身高增长的差异需要进一步调查.
- 长期跟踪至关重要,以确定这些早期生长变异是否会影响未来的疾病风险.
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