新诊断的睡眠呼吸暂停患者中的下呼吸道感染
Jaana Keto1,2, Thijs Feuth3, Miika Linna4,5
1Department of Oral and Maxillofacial Disease, Faculty of Medicine, University of Helsinki, Helsinki, Finland. jaana.keto@gmail.com.
BMC pulmonary medicine
|September 8, 2023
概括
睡眠呼吸暂停患者在诊断一年内面临较高的下呼吸道感染风险. 伴随性疾病对睡眠呼吸暂停患者的感染风险和复发有重大影响.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 睡眠呼吸暂停与慢性疾病和急性健康问题有关.
- 有证据表明,睡眠呼吸暂停可能会增加呼吸道感染的风险和严重程度.
研究的目的:
- 调查与睡眠呼吸暂停诊断有关的下呼吸道感染 (LRTI) 的发生率.
- 分析并发症和患者特征对睡眠呼吸暂停患者LRTI风险和复发的影响.
主要方法:
- 一个芬兰全国性的,以人口为基础的,追溯的病例控制研究.
- 连接国家医疗保健登记册 (2015-2019) 以获得初级和二级保健数据.
- 根据年龄,性别,医院区和多病症来匹配对照组;分析了并发病的独立影响.
主要成果:
- 与对照组相比,睡眠呼吸暂停患者在诊断前 (HR 1.35) 和诊断后 (HR 1.39) 一年内出现较高的LRTI发病率.
- 在诊断前或之后的第二年,没有观察到LRTI发病率的显著差异.
- 在睡眠呼吸暂停患者中,先前存在的LRTI,多病症,COPD,喘和65岁以上的年龄增加了LRTI风险和复发.
结论:
- 睡眠呼吸暂停患者在诊断后一年内患上LRTIs的风险增加,但不会超过.
- 慢性并发症显著影响睡眠呼吸暂停患者中LRTIs的风险和复发.
更多相关视频
相关概念视频
01:21Sleep Apnea
184
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
184
01:17Other Pulmonary Disorders
869
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
869
01:30Tonsillitis I: Introduction
300
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
300
01:31Common Respiratory Disorders
645
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
645
01:30Pneumonia I: Introduction
267
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
267
01:23Acute Respiratory Failure-IV
176
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
176