对于COPD患者的药物和氧疗法进行依从性增强干预:系统性审查和组件网络元分析的协议
Omar Ammous1, Stefan Andreas2,3, Tim Friede4
1Department of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany. Omar.ammous@med.uni-goettingen.de.
Systematic reviews
|September 8, 2023
概括
改善慢性阻塞性肺病 (COPD) 药物治疗的坚持是至关重要的. 本综述评估了加强COPD患者坚持治疗的干预措施,并确定了有效的策略和实施因素.
科学领域:
- 肺部医学 肺部医学
- 医疗保健服务研究 医疗服务研究
- 证据综合 证据综合
背景情况:
- 慢性阻塞性肺病 (COPD) 管理因治疗复杂性和并发症而复杂,影响患者的坚持治疗.
- 慢性肺炎的药物不良服药增加了并发症风险和财务负担.
- 对临床医生来说,评估坚持是具有挑战性的,需要有效的支持策略.
研究的目的:
- 评估旨在改善COPD患者药物服药的干预措施的有效性.
- 确定哪些干预组件对特定的患者子组最有效.
- 探索影响实施的因素和参与者对坚持干预措施的反应.
主要方法:
- 在主要数据库 (Medline,Embase,Cochrane) 中进行全面的文献搜索,无需语言或出版物状态限制.
- 包括所有针对COPD患者增强坚持性干预措施的受控研究.
- 系统性审查方法包括患者参与,双审稿人选,数据提取,偏差风险评估 (ROB 2.0,ROBINS-I),元分析 (对和组件网络),GRADE评估和干预复杂性分析 (iCAT_SR).
主要成果:
- 该部分应在系统审查完成后填写.
结论:
- 这一系统性审查将确定最有效和可实施的COPD增强坚持干预措施.
- 在整个审查过程中患者的参与将确保相关性和适用性.
- 使用复杂干预的先进合成方法将提供基于证据的强有力的建议.
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